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Filtered Search Results
Medchemexpress LLC HY-114091 5mg Medchemexpress, PF-00356231 (hydrochloride) CAS:820223-77-6 Purity:>98%
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Medchemexpress, HY-114091 5mg PF-00356231 (HCl) CAS:820223-77-6 PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). PF-00356231 hydrochloride binds to MMP-12 and forms PF-00356231/MMP-12 complex. PF-00356231 hydrochloride shows potency against MMP-13, MMP-8, MMP-9, MMP-3 with IC50s of 0.00065, 1.7, 0.98, 0.39 μM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-115486 10mg Medchemexpress, MPO-IN-28 CAS:37836-90-1 Purity:>98%
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Medchemexpress, HY-115486 10mg MPO-IN-28 CAS:37836-90-1 MPO-IN-28 (Compound 28) is a myeloperoxidase (MPO) inhibitor with an IC50 of 44 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-111425 10mg Medchemexpress, SSE15206 CAS:1370046-40-4 Purity:>98%
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Medchemexpress, HY-111425 10mg SSE15206 CAS:1370046-40-4 SSE15206 is a microtubule polymerization inhibitor (GI50 = 197 nM in HCT116 cells) that overcomes multidrug resistance. Causes aberrant mitosis resulting in G2/M arrest due to incomplete spindle formation in cancer cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-10914 5mg Medchemexpress, UCPH-101 CAS:1118460-77-7 Purity:>98%
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Medchemexpress, HY-10914 5mg UCPH-101 CAS:1118460-77-7 UCPH-101 is an excitatory amino acid transporter subtype 1 (EAAT1) inhibitor with an IC50 of 0.66 μM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC TFMB-(R)-2-HG | 1445700-01-5 | 98.3% | 50 MG
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TFMB-(R)-2-HG is a cell membrane-permeable (R)-2-HG and an acute myeloid leukemia (AML) oncogenic factor. It functions by competitively inhibiting alpha-ketoglutarate-dependent dioxygenases, such as KDM2B and FTO. This compound impairs cell differentiation when estrogen is withdrawn and is utilized in research concerning acute myeloid leukemia and glioma.
- Cell membrane-permeable (R)-2-HG
- Acute myeloid leukemia (AML) oncogenic factor
- Competitively inhibits alpha-ketoglutarate-dependent dioxygenases (e.g., KDM2B, FTO)
- Impairs cell differentiation upon estrogen withdrawal
- Useful in acute myeloid leukemia research
- Useful in glioma research
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000695712 4 5-DIMETHOXYBENZENE 1G
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Medchemexpress LLC Midodrine-d6 hydrochloride | 1188265-43-1 | 99.4% | 10 MG
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Midodrine-d6 hydrochloride is a selective and orally active adrenergic α1-receptor agonist. It strengthens vascular contraction and is used for research related to cardiovascular diseases, such as orthostatic hypotension. It can also be used as a tracer or an internal standard for quantitative analysis.
- Selective and orally active adrenergic α1-receptor agonist
- Strengthens vascular contraction
- Used in research for cardiovascular diseases
- Can be used as a tracer or internal standard
- Increases p-AMPK and PPARδ expression in certain cells
- Increases Ca2+ in certain cells
- Increases mitochondrial oxidative phosphorylation and ATP content in C2C12 cells
- Reduces cellular lipid content in 3T3-L1 cells
- Exhibits anti-hypotensive effects in orthostatic hypotension rat models
- Relieves hypertension in spontaneously hypertensive rat models
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Chemie Tek PF-06821497 5MG
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PF-06821497 5mg
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Medchemexpress LLC GSK2945 hydrochloride | 00-00-0 | 99.7% | 457.80 g/mol | C20H19Cl3N2O2S | 5 MG
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GSK2945 hydrochloride is the hydrochloride salt of a small-molecule antagonist of the nuclear receptor Rev-erbα, supplied for preclinical research. It has reported EC50 values of 21.5 μM (mouse) and 20.8 μM (human) and has been used to increase CYP7A1 levels and modulate cholesterol metabolism.
- High chemical purity (99.7%).
- Solid form suitable for storage at 4°C; in solution store under nitrogen at -80°C (6 months) or -20°C (1 month).
- Soluble in DMSO (~20.83 mg/mL); in vivo formulations and protocols are available for suspension or clear solution preparations.
- Activity: Rev-erbα antagonist with reported EC50 around 21 μM in cell-based assays.
- Provided for research use with supporting assay and formulation data.
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Medchemexpress LLC LYP-IN-1 | 1404436-51-6 | MFCD34567163 | 99.8% | 501.91 g/mol | C28H20ClNO6 | 5 MG
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LYP-IN-1 is a potent, selective inhibitor of lymphoid tyrosine phosphatase used in biochemical and cellular studies to probe T-cell and mast cell signaling. The compound contains an alkyne moiety enabling copper-catalyzed azide-alkyne cycloaddition for probe development and labeling in chemical biology applications.
- Potent and selective LYP inhibition (Ki 110 nM; IC50 0.259 μM).
- Alkyne handle for copper-catalyzed click chemistry applications.
- High purity suitable for biochemical and cellular assays.
- Soluble in DMSO up to 2 mg/mL with mild heating and sonication.
- Stable when stored as powder at -20°C for extended periods.
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eMolecules 2,3-Dihydroxynaphthalene-1,4-dicarbaldehyde | 103860-60-2 | MFCD09800457 | 100mg
Ambeed | 2,3-Dihydroxynaphthalene-1,4-dicarbaldehyde | 100mg | 595927570 | A730515 | | 103860-60-2 | MFCD09800457 | 216.192 | C12H8O4
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Chem-Impex International, Inc. Diphenyl phosphoryl azide | 26386-88-9 | MFCD00001987 | 25G
Diphenyl phosphoryl azide, 26386-88-9, MFCD00001987, 25G
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Medchemexpress LLC Lrrk2-IN-1 | 1234480-84-2 | 99.0% | 570.69 | 50 MG
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Lrrk2-IN-1 | 1234480-84-2 | 99.0% | 570.69 | 50 MG
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Chem-Impex International, Inc. Diphenyl phosphoryl azide | 26386-88-9 | MFCD00001987 | 100G
Diphenyl phosphoryl azide, 26386-88-9, MFCD00001987, 100G
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eMolecules (S)-(1-Methylazetidin-2-yl)methanamine dihydrochloride | 2682097-49-8 | | 100mg
Ambeed | (S)-(1-Methylazetidin-2-yl)methanamine dihydrochloride | 100mg | 602849439 | A1328848 | | 2682097-49-8 | | 173.080 | C5H14Cl2N2
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